Publications and Presentations

  1. McKenney RJ., Huynh W., Vale RD., and Sirajuddin M. (2016) Tyrosination of α-tubulin controls the initiation of processive dynein-dynactin motility. EMBO J Jun 1;35(11):1175-85. doi:10.15252/embj.201593071. Epub 2016 Mar 11 (bioRxiv)

  2. Nieh S.E., Madou M.R.Z., Sirajuddin M., Fregeau B., McKnight D., Lexa K., Strober J., Spaeth C., Hallinan B., Smaoui N., Pappas J.G., Burrow T.A., McConkie-Rosell A., Latibashvili M., Leshinsky-Silver E., Lev D., Blumkin L., Vale R.D., Barkovich A.J. and Sherr E.H. (2015) De novo mutations in KIF1A cause a syndrome of progressive encephalopathy and brain atrophy. Annals of Clinical and Translational Neurology May 1, 2015 DOI: 10.1002/acn3.198.

  3. Sirajuddin M., Rice LM., and Vale RD. (2014). Regulation of microtubule motors by tubulin isotypes and posttranslational modifications Nature Cell Biology Apr;16(4) 335-44.

  4. Sirajuddin M., Farkasovsky M., Zent E., and Wittinghofer A. (2009). GTP-induced conformational changes in septins and implications for function. PNAS 106(39):16592-7

  5. Gasper R., Meyer S., Gotthardt K., Sirajuddin M., and Wittinghofer A. (2009) It takes two to tango: regulation of G proteins by dimerization. Nature Rev. Mol. Cell Biol 10:423-429

  6. Sirajuddin M., Farkasovsky M., Hauer F., Kuhlmann D., Macara I.G., Weyand M., Stark H., and Wittinghofer A. (2007). Structural insight into filament formation by mammalian septins. Nature 449, 311-5

  7. Prajapati R.S., Das M., Sreeramulu S., Sirajuddin M., Srinivasan S., Krishnamurthy V., Ranjani R., Ramakrishnan C., and Varadarajan R. (2007). Thermodynamic effects of proline introduction on protein stability. Proteins 66, 480-491.

  8. Prajapati R.S., Sirajuddin M., Durani V., Sreeramulu S., and Varadarajan R. (2006). Contribution of cation-pi interactions to protein stability. Biochemistry 45, 15000-15010.